Collaborating with BioJeL on a research project

Promoting scientific research on genetic mental deficiencies

BioJeL offers the scientific community access to its collections.
Access to samples and their associated data is granted under certain conditions. Requests for collaboration are submitted to Biojel Scientific Board which validates their adequacy with its activities.

Most of the projects concern trisomy 21 and associated comorbid conditions

BioJeL is associated with several projects:

DYRK1A and activity-dependent neuroprotective protein comparative diagnosis interest in cerebrospinal fluid and plasma in the context of Alzheimer-related cognitive impairment in Down syndrome patients
Biomedicines, 10 June 2022
Manon Moreau, Maria Carmona-Iragui, Miren Altuna, Lorraine Dalzon, Isabel Barroeta, Marie Vilaire, Sophie Durand, Juan Fortea, Anne-Sophie Rebillat, Nathalie Janel

Identification of 8-Hydroxyquinoline Derivatives That Decrease Cystathionine Beta Synthase (CBS) Activity
International Journal of Molecular Sciences, 17 June 2022
Pierre Conan, Alice Léon, Mathilde Gourdel, Claire Rollet, Loubna Chaïr, Noéline Caroff, Nelig Le Goux, Catherine Le Jossic-Corcos, Maha Sinane, Lucile Gentile, Louise Maillebouis, Nadège Loaëc, Jennifer Martin, Marie Vilaire, Laurent Corcos, Olivier Mignen, Mikael Croyal 2, Cécile Voisset, Frédéric Bihel and Gaëlle Friocourt

Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study)
Genetics in Medicine. 2022 Aug 10
Cécile Cieuta-Walti, Aida Cuenca-Royo, Klaus Langohr, Claire Rakic, Ma Ángeles López-Vílchez, Julián Lirio, Domingo González-Lamuño Leguina, Teresa Bermejo González, Jordi García García, Maria Rimblas Roure, Ana Aldea-Perona, Laura Forcano, Maria Gomis-Gonzalez, Sebastià Videla Cés, Florence Lacaille, Aimé Ravel, Clotilde Mircher, Hervé Walti, Nathalie Janel, Julien Dairou, Marilyne Lévy, Sophie Durand, Mara Dierssen, Silvia Sacco, Rafael de la Torre Fornell, PERSEUS Study Group

  • Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c+ B cells
    Nature, 22 February 2023
    Louise Malle, Roosheel S. Patel, Marta Martin-Fernandez , O’Jay Stewart, Quentin Philippot, Sofija Buta, Ashley Richardson, Vanessa Barcessat , Justin Taft, Paul Bastard, Julie Samuels , Clotilde Mircher, Anne-Sophie Rebillat, Louise Maillebouis, Marie Vilaire-Meunier, Kevin Tuballes, Brad R. Rosenberg, Rebecca Trachtman, Jean-Laurent Casanova, Luigi D. Notarangelo, Sacha Gnjatic, Douglas Bush & Dusan Bogunovic

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